Higher in vivo serotonin‐1a binding in posttraumatic stress disorder: a pet study with [11c]way‐100635

ConclusionsThis is the first report of higher brainstem and forebrain 5‐HT1A binding in vivo in PTSD. The finding is independent of MDD. PTSD and MDD have in common an upregulation of 5‐HT1A binding including midbrain autoreceptors that would favor less firing and serotonin release. This abnormality may represent a common biomarker of these stress‐associated brain disorders. (Source: Depression and Anxiety)

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